Applications for TCRExpress™ and SuperTCRExpress™ products



Our TCRExpress product lines are versatilely usable for the analysis of T lymphocyte immune system responses. Possible applications for our different product groups include:


 
TCR Clonality Detection Kits
  • Detect T cell immune response at the molecular level, and not at the cellular level (as with ELISPOT) or antibody level (as with flow cytomertry), following vaccination or peptide stimulations in vivo or in vitro, and can further characterize antigen specific immune response by CDR3 sequencing.

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  • Track effectiveness of therapeutic treatment in TCR, T cell, gene or anti viral therapy for cancer, autoimmune diseases and HIV infection in human subjects or mouse models.

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  • Monitor T cell immune reconstitution following bone marrow transplantation and combination therapy (HAART).

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  • Support the search for biomarkers for T cell related diseases in human or mouse subjects.

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    TCR Clone Screening Kits
  • Screen TCR clones in established monoclonal T cell lines, such as CTL clone, or Tumor T cell line.

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  • Determine gene expression of individual TCR Vα/β family.

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    Clonality Quantitation and CDR3 Size Diversity Determination
  • Measure T cell immune response quantitativly at the molecular level, and not at the cellular level (as with ELISPOT) or antibody level (as with flow cytomertry), following vaccination or peptide stimulations in vivo or in vitro, and can further characterize antigen specific immune response by CDR3 sequencing.

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  • Track quantitatively the effectivess of therapeutic treatment in TCR, T cell, gene or anti viral therapy for cancer, autoimmune diseases and HIV infection in human subjects or mouse models.

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  • Monitor quantitatively T cell immune reconstitution following bone marrow transplantation and combination therapy (HAART).

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  • Supports the search for biomarkers for T cell related diseases in human or mouse subjects through quantitative analysis.

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